rheumatism

Noun
  1. Any painful disorder of the joints or muscles or connective tissues (synset 114103692)
  2. A chronic autoimmune disease with inflammation of the joints and marked deformities;
    Something (possibly a virus) triggers an attack on the synovium by the immune system, which releases cytokines that stimulate an inflammatory reaction that can lead to the destruction of all components of the joint (synset 114210220)

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