aggravation

Noun
  1. An exasperated feeling of annoyance (synset 107534117)
    hypernym: annoyance, chafe, vexation - anger produced by some annoying irritation
    synonym: exasperation
  2. Unfriendly behavior that causes anger or resentment (synset 101224279)
    hypernym: aggression - deliberately unfriendly behavior
    hyponym:
    • aggro - (informal British usage) aggravation or aggression
    • last straw - the final irritation that stretches your patience beyond the limit
    • taunt, taunting, twit - aggravation by deriding or mocking or criticizing
    synonym: irritation, provocation
  3. Action that makes a problem or a disease (or its symptoms) worse (synset 100375643)
    "the aggravation of her condition resulted from lack of care"
    hypernym: intensification - action that makes something stronger or more extreme
    synonym: exacerbation

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