isolation

Noun
  1. A state of separation between persons or groups (synset 114438119)
  2. A feeling of being disliked and alone (synset 107517815)
  3. The act of isolating something;
    Setting something apart from others (synset 101204519)
  4. (psychiatry) a defense mechanism in which memory of an unacceptable act or impulse is separated from the emotion originally associated with it (synset 113524876)
  5. A country's withdrawal from international politics (synset 101242282)
    "he opposed a policy of American isolation"

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