grievous

Adjective
  1. Causing fear or anxiety by threatening great harm (synset 300654061)
    "a dangerous operation"; "a grave situation"; "a grave illness"; "grievous bodily harm"; "a serious wound"; "a serious turn of events"; "a severe case of pneumonia"; "a life-threatening disease"
  2. Causing or marked by grief or anguish (synset 301368460)
    "a grievous loss"; "a grievous cry"; "her sigh was heartbreaking"; "the heartrending words of Rabin's granddaughter"
  3. Of great gravity or crucial import;
    Requiring serious thought (synset 301281533)
    "grave responsibilities"; "faced a grave decision in a time of crisis"; "a grievous fault"; "heavy matters of state"; "the weighty matters to be discussed at the peace conference"
  4. Shockingly brutal or cruel (synset 301134954)
    "murder is an atrocious crime"; "a grievous offense against morality"; "a grievous crime"; "no excess was too monstrous for them to commit"

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