1. The principal character in a work of fiction (synset 110192465)
  2. Someone involved in a contest or battle (as in an agon) (synset 109798721)
  3. A muscle that contracts while another relaxes (synset 105300767)
    "when bending the elbow the biceps are the agonist"
  4. (biochemistry) a drug that can combine with a receptor on a cell to produce a physiological reaction (synset 102687648)

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