despair

Noun
  1. A state in which all hope is lost or absent (synset 114509858)
    "in the depths of despair"; "they were rescued from despair at the last minute"; "courage born of desperation"
  2. The feeling that everything is wrong and nothing will turn out well (synset 107557311)
    "they moaned in despair and dismay"; "one harsh word would send her into the depths of despair"
Verb
  1. Abandon hope;
    Give up hope;
    Lose heart (synset 201814900)
    "Don't despair--help is on the way!"

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